Córtex cingulado anterior e sua relação com autismo

Abstract

This bibliographical study aims to discuss the relation of the Autistic Spectrum Disorder (ASD) with the anterior cingulate cortex, understanding how it is epigenetically related. Being an underdiagnosed disorder, mainly in adults, autism presents an increased incidence in the world, since the last reported researches. Because its symptomatology is very heterogeneous, several studies have tried to understand its pathophysiological development. Thus, based on theoretical references found in books and data search platforms, such as Pubmed, the present research will analyze articles from the year 2017-2021, using as keywords: autism and anterior cingulate cortex, seeking to establish a relationship of the neurological structure with the syndrome, emphasizing the pathways involved in this process, as well as the interference in the social life of individuals from these findings. From the analysis, it was noticed that there are several genes related to the anterior cingulate cortex and that it is intrinsically related to autism. Furthermore, several studies have raised discussions about a propaedeutic capable of interfering in the development of this disorder, seeking to establish early and emphatic diagnoses, in addition to more targeted treatments, in order to promote an improvement in the quality of life and health promotion of these individuals. Therefore, this study proves an epigenetic inheritance present in ASD, and due to the few studies on the subject, it justifies this research being so important nowadays.