Potencial aplicação de β- GLUCANOS de Pleurotus ostreatoroseus por meio de nanopartículas: uma revisão da literatura

Abstract

The Pleurotus ostreatoroseus mushroom is a native species, popularly knowm as pink shimeji. Marketed worldwide, they have great relevance in the current scenario, being able to contribute in the sustainable development of functional foods and new medcines. The chemical characterization and bioactivity of this species of basidiomycete showed that its βglucan polysaccharides, presente effects on the imune system acting as immunomodulators and antimutagenics. Thus, the current bibliographic review was carried out in order to discuss the possible applications of this polysaccharide in disease treatments and preventions. Therefore, a scan about biological effects of β-glucans as well the use of nanotechnology to optimize applications in biological systems have been made, noting that glucans are relevant in order to function as nanoparticles carriers, due to being used as reducing adents and stabilizing metal ions. Nanoparticle formulations when encapsulated facilitate absorption in the delivery tissues, due to their nanoscopic scale. Thus, the dofferent mechanisms of βglucans of the basidiomycete and their possible application in the body were addressed in this bibliographic review, showing that it is possible to encapsulate it. However, it is important to certify the recommendations onsafety and/or risks associated with its in vivo consumption while elucidating its nutraceutical characteristics.