O uso da L-PRF no tratamento da osteonecrose dos maxilares: revisão de literatura

Abstract

Maxillary osteonecrosis is a rare but serious clinical condition, often associated with the use of antiresorptive and antiangiogenic medications. Although treatment protocols remain uncertain, leukocyte- and platelet-rich fibrin (L-PRF) has emerged as a promising option. L-PRF, being autologous and biocompatible, aids in tissue regeneration through the prolonged release of growth factors, promoting angiogenesis, osteogenesis, and inflammatory homeostasis. This study, conducted through a literature review using databases such as PubMed, SciELO, and Google Scholar, aims to clarify the benefits of using L-PRF in dentistry, with an emphasis on its application in the treatment of maxillary osteonecrosis. The results suggest that the use of L PRF, in conjunction with surgical treatment, provides high healing rates and symptom reduction, making it a relevant therapeutic approach for treating this condition in stages II and III.