Aspectos éticos envolvidos no desenvolvimento das vacinas contra a COVID-19: uma revisão integrativa da literatura

Abstract

Introduction: The development of a vaccine against SARS-Cov-2 in the current context turns out to be the main strategy for the end of the pandemic, the complete economic reopening and the normalization of social activities and health systems. Objective: In view of the importance of an effective and safe vaccine, which is necessary for commercialization and massive distribution, the project aimsto analyze the bioethical and social aspects about the modifications and adaptations of new schemes, testing trials and distribution logistics of COVID-19 vaccine, which introduce potential risks to their recipients. Method: It is a bibliographic research, descriptive and exploratory, by using integrative literature review tools, based on articles data collected from the platforms: Scielo, Pubmed and Web of Science. The data analysis was divided in three consecutive steps: 1) articles screening by means of Rayyan, 2) screening of articles selected on the first step, and 3) reading and analysis of the articles for the final sample of integrative review, with help of the software QSR NVIVO 12. Results: The necessity of adaption to the demands of the COVID-19 pandemic, directly interfered in the field of research, and traditional processes of clinical trials of vaccines, as well as raised questions regarding social equity notions in the face of limited resources. Final considerations: The ethical values are important guides for conducting the development and distribution of the COVID-19 vaccine, aiming the principle of equity of access to health.