Papel dos fatores de risco na identificação de indivíduos ao rastreamento do câncer de pâncreas: revisão sistemática

Abstract

Introduction: Pancreatic adenocarcinoma is considered one of the tumors with the worst prognosis, owin to your aggressiveness and low resectability rate due to its diagnosis being, in most cases, in advanced stages. Objective: to synthesize the main research results and critically analyze the evidence about how risk factors can contribute to the selection of individuals who would benefit from pancreatic cancer screening in the international scientific literature in the last five years. Methods: a search was performed in the MEDLINE and Lilacs databases with the following descriptors: "pancreatic cancer" or "pancreatic neoplasm" always combined with "screening" and "risk factors". Ten articles published in international journals were selected and their results were described. Results: There is evidence in the literature that individuals with chronic hereditary pancreatitis or family history of the disease would benefit from screening for pancreatic cancer. Conclusion: The results indicate several risk factors related to the development of pancreatic cancer and the need for further studies, with greater methodological rigor and results with higher levels of scientific evidence.